📢The official Croaie® flagship store: Products are patented. Counterfeiting will be prosecuted.

The supramolecular collaborative drug delivery method used in Croaie® eye drops isn't just clever—it's the result of years of intensive research by multiple experts and scientists in the fields of ophthalmology, chemistry, and molecular medicine. It's supported by peer-reviewed publications.

And this isn't just theory—it's an innovation that has garnered recognition. In 2023, this technology received the Edison Silver Award, a recognition of excellence in applied science and innovation.

Our eye drops have been clinically tested by ophthalmology experts and proven effective in significantly improving eye health within 1-3 weeks
relieving discomfort, increasing eye comfort, and showing results within 2-7 days.

       Let's take a look at what makes Croaie® supramolecular eye drops so special.

Croaie® Supramolecular Eye Drops utilize advanced supramolecular composite technology. Applying the principle of non-covalent self-assembly, various active ingredients are encapsulated into a nanoscale supramolecular network, ensuring precise delivery to the target areas of the eye. This significantly improves the stability, permeability, and bioavailability of the drug.

This composite technology enables sustained release after the drug enters the eye and effectively penetrates the corneal and conjunctival barriers. It reduces drug loss, decreases application frequency, and enhances therapeutic effects.

The supramolecular composite structure adheres closely to the corneal surface, helps restore the elasticity and shape of the lens, improves the nutrient supply to the eye cells, and promotes the elimination of metabolic waste, thereby improving overall eye health. It also possesses a short-term pupil regulation function that helps improve near vision while maintaining distance vision.

Let's take a look at real reviews from users after using the product.

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"I developed cataracts in one eye, and they've been progressing for about five or six years. Although I was waiting for surgery, I was always hesitant to have my lens removed. Then I came across Croaie® eye drops online, and to my surprise, after just two weeks of use, I noticed a significant improvement in my vision—the blurry feeling I used to wake up with in the morning began to fade.

Now, after two months, my vision has noticeably improved. I can use my phone comfortably again and even drive with confidence. I'm truly grateful for Croaie®—it has helped me regain clarity and freedom in my daily life." — James Anderson

"I started seeing these small black dots and thread-like floaters in my field of vision last year—especially when I looked at bright backgrounds like the sky or a white wall. My ophthalmologist said they were just floaters, but honestly, it was really bothering me. I found it hard to concentrate, and sometimes my vision felt completely messed up.

I came across these eye drops online that had lots of good reviews and thought, why not try them? I used them every day, and after about the third week, I actually started to notice a difference. The floaters weren't as bad, and my eyes didn't feel as dry either.

It's been almost two months now, and my floaters are completely gone. My vision feels much clearer." — Robert Walker

"I have retinopathy and get eye injections every eight weeks. I've had 13 so far, and the doctor said I might need them for the rest of my life. But since I started using Croaie® eye drops daily, everything has changed. After two months, I went for a check-up, and the doctor said my eyes look great—no leakage at all. For the first time ever, I didn't need another injection. I'm really grateful for Croaie®. It has given me real hope." — Mark Reynolds

"I've suffered from severe dry eyes for 25 years and tried many different eye drops, but almost none helped. Each time I used them, the relief only lasted a few seconds to a minute at most; the drops just wouldn't stay in place, and my eyes continued to hurt. I couldn't even watch TV during the day, and on cloudy or rainy days, I had to wear sunglasses because my eyes were so sensitive. I even had to quit my job as a truck driver because of these problems.

After a friend recommended Croaie® eye drops, I tried them. After just a few days, my eyes felt much better. Unlike other drops, Croaie® provides long-lasting relief and reduces light sensitivity during the day.

If, like me, you've struggled with dry eyes for years, I highly recommend Croaie®. It's unlike anything I've tried." — David Thompson

What can our eye drops offer you?

Understanding common eye diseases:

Presbyopia typically begins around age 40. As the lens inside the eye gradually loses its elasticity and ability to focus, near vision deteriorates. Presbyopia interferes with daily life, especially when reading or using a computer. Croaie® eye drops can penetrate the eye, restore the elasticity of the lens, and improve near vision. After use, everyday tasks like reading and using a computer become much easier, with clearer vision.

Cataracts are among the most common eye diseases in older people and typically occur when the transparent structure of the eye—the lens—becomes cloudy, causing vision to gradually become blurred or blurry. The formation of cataracts is typically caused by aging, UV exposure, and diabetes. Cataracts are a progressive but reversible disease. Croaie® eye drops utilize advanced supramolecular technology to specifically target the lens, breaking down the cloudy aggregations at the molecular level and temporarily restoring its transparency, thereby improving vision.

Glaucoma is a disease caused by increased intraocular pressure, which leads to optic nerve damage. It often shows no noticeable symptoms in the early stages, so many patients don't notice the problem until their vision begins to deteriorate.

Croaie® eye drops utilize advanced supramolecular composite technology that improves the regulation of fluid dynamics in the eye by promoting efficient outflow and effectively reducing intraocular pressure. The supramolecular composites enable the controlled and sustained release of active ingredients such as L-carnitine to slow the progression of glaucoma. This provides patients with a safe, non-invasive, and highly effective treatment option.

Dry eye syndrome is an eye condition caused by insufficient tear production or an unstable tear film. It often manifests as dry eyes, a foreign body sensation, burning, and wind sensitivity. With age, the function of the tear glands gradually declines. If left untreated, the symptoms of dry eye syndrome can lead to corneal injury and impair vision. Our eye drops not only provide immediate relief from the symptoms of dry eyes but also provide long-lasting lubrication, helping to stabilize the tear film and alleviating discomfort, making your eyes feel more comfortable.

Diabetic retinopathy is a common eye complication in diabetics caused by long-term high blood sugar levels, which damage the retinal microvessels and lead to leakage, bleeding, or the formation of new blood vessels. In severe cases, it can lead to vision loss. After five years of diabetes, the disease reaches a high-risk stage, and 70% of patients with type 2 diabetes could lose their vision. Croaie® eye drops utilize advanced supramolecular composite technology to overcome the challenge of conventional eye drops' inability to effectively deliver medication to the posterior tissues of the eye. They can penetrate deep into the retina to effectively reduce retinal swelling, constrict blood vessels, and stop leakage. This helps restore vision, slow the progression of diabetic retinopathy, and reduce the risk of vision loss.

Flying flies are a common phenomenon in the eye and appear as small dark spots, lines, or cobweb-like shapes that drift across the field of vision—like tiny insects flying in front of the eyes. They are particularly noticeable when looking at bright backgrounds such as a white wall or the sky and are usually caused by a slight clouding in the vitreous humor of the eye. Our eye drops can help relieve and improve this condition.

💧How do Croaie® Supramolecular Eye Drops work?

Croaie® works primarily by restoring lens elasticity, improving cellular nutrition in the eye, and removing accumulated cellular debris.

Croaie® utilizes advanced supramolecular technology, in which active ingredients are stably encapsulated in supramolecular carrier systems through non-covalent interactions such as hydrogen bonds, electrostatic forces, and hydrophobic effects. These structures can efficiently penetrate the corneal barrier and reach deeper ocular tissues. Compared to traditional carrier systems, supramolecular systems can respond to local ocular conditions—such as changes in pH or temperature—enabling targeted, on-demand drug delivery to affected areas, thereby enhancing therapeutic efficacy.

In addition, Croaie® contains a precisely balanced pH formula that mimics the natural tear film, providing long-lasting lubrication, relieving dryness, and forming a protective barrier for the eyes.

This technology significantly improves the stability, penetration, and targeting of the medication in the eye, allowing it to penetrate deep into the back of the eye to reduce intraocular pressure, restore lens elasticity, and repair retinal tissue. The formula is gentle, pH-balanced with the tear film, making it safe for long-term use and non-irritating.

Multiple active ingredients:

Spirulina: Spirulina is rich in high concentrations of zeaxanthin, which is mainly concentrated in the central area of the macula, the part of the eye responsible for sharp vision. Zeaxanthin plays a key role in filtering blue light and UV rays and helps protect against photooxidative damage. With age, the macula becomes more vulnerable to damage from blue light and UV radiation, which can lead to problems such as blurred vision, cataracts, or macular degeneration. Supplementing with zeaxanthin helps slow the visual aging process and protect the structure of the macula.

N-Acetylcysteine (NAC): NAC promotes the production of glutathione, which helps protect the retina and nerve cells from oxidative stress. This is especially important for glaucoma patients, as their optic nerves can be damaged. NAC activates adult stem cells and supports the natural repair and regeneration of damaged eye tissue, including the retina, optic nerve, and lens.

Pirenzepine: Pirenzepine is a key ingredient in the treatment of myopia. It works by inhibiting excessive contraction of the eye muscles, which slows the excessive growth of the eyeball. This helps control the progression of myopia and prevents further changes in the shape of the eyeball. Long-term use of this ingredient can effectively slow the progression of myopia.

Resveratrol: Resveratrol is a natural polyphenolic compound that is beneficial for microcirculation in the eye and helps prevent eye diseases such as age-related macular degeneration, diabetic retinopathy, and glaucoma. Studies have shown that resveratrol has antioxidant, anti-apoptotic, anti-tumor, anti-inflammatory, anti-angiogenic, and vasodilatory properties.

Brimonidine: Brimonidine is an active ingredient in eye drops that is particularly effective in treating dry eye syndrome. It works by reducing the dilation of blood vessels in the eye, thereby relieving redness and discomfort. Brimonidine also helps reduce excessive dryness and irritation, keeping the eyes moist and improving the symptoms of dry eyes. It is especially beneficial for relieving dryness caused by prolonged use of electronic devices or extended exposure to air-conditioned environments.